/* ============================================================
   PREXIVA LIFESCIENCES — Design System
   Nature, Refined by Science.
   ============================================================ */

@font-face {
  font-family: "Fraunces";
  src: url("/assets/fonts/fraunces-latin-full-normal.woff2") format("woff2-variations");
  font-weight: 100 900;
  font-style: normal;
  font-display: swap;
}
@font-face {
  font-family: "Fraunces";
  src: url("/assets/fonts/fraunces-latin-full-italic.woff2") format("woff2-variations");
  font-weight: 100 900;
  font-style: italic;
  font-display: swap;
}
@font-face {
  font-family: "Inter";
  src: url("/assets/fonts/inter-latin-wght-normal.woff2") format("woff2-variations");
  font-weight: 100 900;
  font-style: normal;
  font-display: swap;
}

:root {
  /* Primary */
  --navy-950: #081418;
  --teal-950: #0A1D22;
  --teal-900: #0E2429;
  --teal-800: #143038;
  --teal-700: #1C4049;
  --ink: #12262C;

  /* Secondary */
  --emerald: #2E6656;
  --emerald-soft: #3E7A67;
  --aqua: #8FBDB6;
  --molecular: #A9C4D2;
  --ivory: #F7F4EC;
  --paper: #FBFAF5;
  --white: #FFFFFF;

  /* Accent */
  --copper: #B0763B;
  --gold: #D2A24C;
  --gold-bright: #E3B863;
  --amber: #C98F35;

  /* Neutral */
  --charcoal: #1F282C;
  --slate: #5A6B70;
  --slate-light: #81959B;
  --mist: #E9E6DC;
  --line: rgba(18, 38, 44, 0.12);
  --line-dark: rgba(247, 244, 236, 0.14);

  /* Type */
  --serif: "Fraunces", Georgia, serif;
  --sans: "Inter", -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;

  --radius: 18px;
  --radius-sm: 12px;
  --shadow-soft: 0 18px 50px -18px rgba(8, 20, 24, 0.22);
  --shadow-card: 0 10px 34px -14px rgba(8, 20, 24, 0.16);
  --gutter: clamp(1.25rem, 4.5vw, 4rem);
  --section-pad: clamp(4.5rem, 9vw, 8.5rem);
}

/* ---------- Reset ---------- */
*, *::before, *::after { box-sizing: border-box; margin: 0; padding: 0; }
html { scroll-behavior: smooth; -webkit-text-size-adjust: 100%; }
body {
  font-family: var(--sans);
  font-size: 1.0625rem;
  line-height: 1.7;
  color: var(--charcoal);
  background: var(--paper);
  -webkit-font-smoothing: antialiased;
  overflow-x: hidden;
}
img, video { max-width: 100%; display: block; }
a { color: inherit; text-decoration: none; }
ul { list-style: none; }
button { font: inherit; cursor: pointer; background: none; border: none; }
::selection { background: rgba(210, 162, 76, 0.35); }

h1, h2, h3, .serif {
  font-family: var(--serif);
  font-weight: 480;
  line-height: 1.12;
  letter-spacing: -0.015em;
  color: var(--ink);
}

.wrap { width: min(1200px, 100% - 2 * var(--gutter)); margin-inline: auto; }
.wrap-wide { width: min(1360px, 100% - 2 * var(--gutter)); margin-inline: auto; }

section { position: relative; }
.section { padding-block: var(--section-pad); }

/* ---------- Type scale ---------- */
.display {
  font-size: clamp(2.6rem, 6.2vw, 4.6rem);
  line-height: 1.04;
}
.h2 { font-size: clamp(1.9rem, 3.8vw, 2.9rem); }
.h3 { font-size: clamp(1.28rem, 2vw, 1.6rem); font-weight: 520; }
.lead { font-size: clamp(1.1rem, 1.6vw, 1.3rem); line-height: 1.65; color: var(--slate); }
.eyebrow {
  font-family: var(--sans);
  font-size: 0.78rem;
  font-weight: 650;
  letter-spacing: 0.22em;
  text-transform: uppercase;
  color: var(--copper);
  display: inline-flex;
  align-items: center;
  gap: 0.75rem;
  margin-bottom: 1.2rem;
}
/* decorative pre-line intentionally removed */
.sub-serif {
  font-family: var(--serif);
  font-style: italic;
  font-weight: 420;
  color: var(--gold);
  font-size: clamp(1.15rem, 2vw, 1.5rem);
  letter-spacing: 0.01em;
}

/* on dark */
.on-dark, .on-dark h1, .on-dark h2, .on-dark h3 { color: var(--ivory); }
.on-dark .lead { color: rgba(247, 244, 236, 0.78); }
.on-dark .eyebrow { color: var(--gold); }

/* ============================================================
   HEADER
   ============================================================ */
.site-header {
  position: fixed;
  inset: 0 0 auto 0;
  z-index: 140;
  background: rgba(251, 250, 245, 0.92);
  -webkit-backdrop-filter: blur(14px);
  backdrop-filter: blur(14px);
  border-bottom: 1px solid rgba(18, 38, 44, 0.08);
  transition: background 0.45s ease, box-shadow 0.45s ease, padding 0.4s ease;
  padding-block: 0.95rem;
}
.site-header.scrolled {
  background: rgba(251, 250, 245, 0.97);
  box-shadow: 0 10px 30px -18px rgba(8, 20, 24, 0.25);
  padding-block: 0.6rem;
}
.header-inner {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 2rem;
}
.brand { display: flex; align-items: center; gap: 0.7rem; }
.brand-logo {
  height: 46px;
  width: auto;
  display: block;
  transition: height 0.35s ease;
}
.site-header.scrolled .brand-logo { height: 38px; }
.footer-logo { width: min(240px, 100%); height: auto; display: block; }
.footer-logo-plate {
  display: inline-block;
  background: var(--paper);
  padding: 1.15rem 1.35rem 1rem;
  border-radius: 14px;
  box-shadow: 0 12px 32px -16px rgba(0, 0, 0, 0.5);
}
.section-video {
  display: block;
  width: 100%;
  border-radius: calc(var(--radius) + 6px);
  box-shadow: var(--shadow-soft);
}
.brand-mark { width: 38px; height: 38px; flex: none; }
.brand-text { display: flex; flex-direction: column; line-height: 1.05; }
.brand-name {
  font-family: var(--serif);
  font-size: 1.42rem;
  font-weight: 540;
  color: var(--ivory);
  letter-spacing: 0.01em;
}
.brand-sub {
  font-size: 0.58rem;
  font-weight: 650;
  letter-spacing: 0.34em;
  text-transform: uppercase;
  color: var(--gold);
}
.main-nav { display: flex; align-items: center; gap: clamp(1.1rem, 2.2vw, 2.1rem); }
.main-nav a {
  font-size: 0.92rem;
  font-weight: 560;
  color: var(--slate);
  position: relative;
  padding-block: 0.35rem;
  transition: color 0.25s ease;
}
.main-nav a::after {
  content: "";
  position: absolute;
  left: 0; bottom: 0;
  width: 100%; height: 1.5px;
  background: var(--gold);
  transform: scaleX(0);
  transform-origin: left;
  transition: transform 0.3s ease;
}
.main-nav a:hover, .main-nav a.active { color: var(--ink); }
.main-nav a:hover::after, .main-nav a.active::after { transform: scaleX(1); }

.btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 0.6rem;
  padding: 0.85rem 1.7rem;
  border-radius: 999px;
  font-size: 0.93rem;
  font-weight: 620;
  letter-spacing: 0.02em;
  transition: transform 0.28s ease, box-shadow 0.28s ease, background 0.28s ease, color 0.28s ease, border-color 0.28s ease;
  will-change: transform;
}
.btn svg { transition: transform 0.28s ease; }
.btn:hover svg { transform: translateX(4px); }
.btn-gold {
  background: linear-gradient(120deg, var(--gold) 0%, var(--copper) 100%);
  color: var(--navy-950);
  box-shadow: 0 10px 26px -10px rgba(210, 162, 76, 0.55);
}
.btn-gold:hover { transform: translateY(-2px); box-shadow: 0 16px 34px -10px rgba(210, 162, 76, 0.65); }
.btn-ghost {
  border: 1.5px solid rgba(247, 244, 236, 0.35);
  color: var(--ivory);
}
.btn-ghost:hover { border-color: var(--gold); color: var(--gold-bright); transform: translateY(-2px); }
.btn-dark {
  background: var(--ink);
  color: var(--ivory);
}
.btn-dark:hover { transform: translateY(-2px); box-shadow: 0 14px 30px -12px rgba(8, 20, 24, 0.45); }
.btn-outline-dark {
  border: 1.5px solid rgba(18, 38, 44, 0.28);
  color: var(--ink);
}
.btn-outline-dark:hover { border-color: var(--copper); color: var(--copper); transform: translateY(-2px); }
.header-cta { display: inline-flex; }

/* Mobile nav */
.nav-toggle {
  display: none;
  flex-direction: column;
  gap: 5.5px;
  padding: 0.5rem;
  z-index: 140;
}
.nav-toggle span {
  width: 26px; height: 2px;
  background: var(--ink);
  border-radius: 2px;
  transition: transform 0.35s ease, opacity 0.3s ease;
}
.nav-toggle.open span:nth-child(1) { transform: translateY(7.5px) rotate(45deg); }
.nav-toggle.open span:nth-child(2) { opacity: 0; }
.nav-toggle.open span:nth-child(3) { transform: translateY(-7.5px) rotate(-45deg); }

.mobile-menu {
  position: fixed;
  inset: 0;
  z-index: 130;
  background: linear-gradient(165deg, var(--paper), var(--ivory));
  display: flex;
  flex-direction: column;
  justify-content: center;
  padding: 6rem var(--gutter) 3rem;
  opacity: 0;
  pointer-events: none;
  transition: opacity 0.4s ease;
}
.mobile-menu.open { opacity: 1; pointer-events: auto; }
.mobile-menu a {
  font-family: var(--serif);
  font-size: clamp(1.8rem, 7vw, 2.6rem);
  color: var(--ink);
  padding-block: 0.55rem;
  border-bottom: 1px solid var(--line);
  opacity: 0;
  transform: translateY(18px);
  transition: opacity 0.45s ease, transform 0.45s ease, color 0.3s ease;
}
.mobile-menu.open a { opacity: 1; transform: translateY(0); }
.mobile-menu a:hover, .mobile-menu a.active { color: var(--copper); }
.mobile-menu .menu-contact {
  margin-top: 2rem;
  font-family: var(--sans);
  font-size: 0.95rem;
  color: var(--slate);
}
.mobile-menu .menu-contact a {
  font-family: var(--sans);
  font-size: 0.95rem;
  border: none;
  display: inline;
  padding: 0;
  color: var(--copper);
}

@media (max-width: 920px) {
  .main-nav, .header-cta { display: none; }
  .nav-toggle { display: flex; }
}

/* ============================================================
   HERO (home)
   ============================================================ */
.hero {
  position: relative;
  min-height: 100svh;
  display: flex;
  align-items: center;
  background: var(--navy-950);
  overflow: hidden;
  color: var(--ivory);
}
.hero-media, .hero-media video, .hero-canvas {
  position: absolute;
  inset: 0;
  width: 100%;
  height: 100%;
}
.hero-media video, .hero-media img.hero-fallback {
  object-fit: cover;
  object-position: 62% center;
  width: 100%;
  height: 100%;
}
.hero-canvas { opacity: 0; transition: opacity 2.5s ease; pointer-events: none; }
.hero-canvas.on { opacity: 0.55; }
.hero-scrim {
  position: absolute;
  inset: 0;
  background:
    linear-gradient(100deg, rgba(8, 20, 24, 0.9) 0%, rgba(8, 20, 24, 0.62) 38%, rgba(8, 20, 24, 0.18) 68%, rgba(8, 20, 24, 0.38) 100%),
    linear-gradient(to top, rgba(8, 20, 24, 0.85) 0%, transparent 32%);
}
.hero-content {
  position: relative;
  z-index: 2;
  padding-block: 9rem 6rem;
  max-width: 720px;
}
.hero-content .display { color: var(--ivory); margin-bottom: 1.1rem; }
.hero-content .display .accent {
  color: var(--gold-bright);
  font-style: italic;
  font-weight: 420;
}
.hero-lede {
  font-size: clamp(1.05rem, 1.5vw, 1.22rem);
  color: rgba(247, 244, 236, 0.82);
  max-width: 56ch;
  margin-block: 1.4rem 2.2rem;
}
.hero-ctas { display: flex; flex-wrap: wrap; gap: 0.9rem; margin-bottom: 2.6rem; }
.hero-chips { display: flex; flex-wrap: wrap; gap: 0.6rem; }
.chip {
  display: inline-flex;
  align-items: center;
  gap: 0.5rem;
  font-size: 0.78rem;
  font-weight: 600;
  letter-spacing: 0.06em;
  padding: 0.48rem 0.95rem;
  border-radius: 999px;
  border: 1px solid rgba(247, 244, 236, 0.22);
  color: rgba(247, 244, 236, 0.85);
  background: rgba(8, 20, 24, 0.35);
  -webkit-backdrop-filter: blur(6px);
  backdrop-filter: blur(6px);
}
.chip::before {
  content: "";
  width: 6px; height: 6px;
  border-radius: 50%;
  background: var(--gold);
}
.scroll-cue {
  position: absolute;
  bottom: 2.2rem;
  left: 50%;
  transform: translateX(-50%);
  z-index: 2;
  display: flex;
  flex-direction: column;
  align-items: center;
  gap: 0.5rem;
  color: rgba(247, 244, 236, 0.6);
  font-size: 0.72rem;
  letter-spacing: 0.28em;
  text-transform: uppercase;
}
.scroll-cue .line {
  width: 1.5px; height: 46px;
  background: linear-gradient(to bottom, transparent, var(--gold));
  animation: cueDrop 2.2s ease-in-out infinite;
  transform-origin: top;
}
@keyframes cueDrop {
  0% { transform: scaleY(0); opacity: 0; }
  35% { transform: scaleY(1); opacity: 1; }
  100% { transform: scaleY(1) translateY(10px); opacity: 0; }
}

/* Interior page hero */
.page-hero {
  position: relative;
  background:
    radial-gradient(1100px 500px at 85% -10%, rgba(46, 102, 86, 0.35), transparent 60%),
    radial-gradient(900px 480px at -10% 110%, rgba(176, 118, 59, 0.22), transparent 55%),
    linear-gradient(150deg, var(--navy-950) 10%, var(--teal-900) 55%, var(--teal-800) 100%);
  color: var(--ivory);
  padding: clamp(9rem, 16vw, 12.5rem) 0 clamp(4rem, 8vw, 6.5rem);
  overflow: hidden;
}
.page-hero .display { color: var(--ivory); max-width: 16ch; }
.page-hero .lead { max-width: 62ch; margin-top: 1.4rem; }
.page-hero-canvas {
  position: absolute; inset: 0;
  width: 100%; height: 100%;
  opacity: 0.5;
  pointer-events: none;
}
.page-hero .wrap { position: relative; z-index: 2; }

/* ============================================================
   SECTIONS & COMPONENTS
   ============================================================ */
.sect-head { max-width: 780px; margin-bottom: clamp(2.4rem, 5vw, 4rem); }
.sect-head.center { margin-inline: auto; text-align: center; }
.sect-head.center .eyebrow { justify-content: center; }
.sect-head .h2 { margin-bottom: 1rem; }

.bg-dark {
  background:
    radial-gradient(1000px 500px at 90% 0%, rgba(46, 102, 86, 0.28), transparent 55%),
    radial-gradient(800px 400px at 5% 100%, rgba(176, 118, 59, 0.16), transparent 50%),
    linear-gradient(160deg, var(--navy-950), var(--teal-900) 70%);
}
.bg-ivory { background: var(--ivory); }
.bg-paper { background: var(--paper); }
.bg-mist { background: linear-gradient(to bottom, var(--paper), var(--ivory)); }

/* Grid helpers */
.grid-2 { display: grid; grid-template-columns: repeat(2, 1fr); gap: clamp(1.4rem, 3vw, 2.6rem); }
.grid-3 { display: grid; grid-template-columns: repeat(3, 1fr); gap: clamp(1.2rem, 2.4vw, 2rem); }
.grid-4 { display: grid; grid-template-columns: repeat(4, 1fr); gap: clamp(1.1rem, 2vw, 1.6rem); }
@media (max-width: 980px) {
  .grid-3, .grid-4 { grid-template-columns: repeat(2, 1fr); }
}
@media (max-width: 640px) {
  .grid-2, .grid-3, .grid-4 { grid-template-columns: 1fr; }
}

/* Cards */
.card {
  background: var(--white);
  border: 1px solid var(--line);
  border-radius: var(--radius);
  padding: clamp(1.6rem, 2.6vw, 2.2rem);
  box-shadow: var(--shadow-card);
  transition: transform 0.35s ease, box-shadow 0.35s ease, border-color 0.35s ease;
  position: relative;
  overflow: hidden;
}
.card:hover { transform: translateY(-6px); box-shadow: var(--shadow-soft); border-color: rgba(176, 118, 59, 0.35); }
.card .h3 { margin-block: 0.9rem 0.6rem; }
.card p { color: var(--slate); font-size: 0.98rem; }
.card-icon {
  width: 52px; height: 52px;
  border-radius: 14px;
  display: grid;
  place-items: center;
  background: linear-gradient(140deg, rgba(46, 102, 86, 0.12), rgba(210, 162, 76, 0.14));
  color: var(--emerald);
}
.card-icon svg { width: 26px; height: 26px; }
.card-link {
  display: inline-flex;
  align-items: center;
  gap: 0.45rem;
  margin-top: 1.1rem;
  font-size: 0.88rem;
  font-weight: 650;
  color: var(--copper);
}
.card-link svg { transition: transform 0.25s ease; }
.card:hover .card-link svg { transform: translateX(4px); }

/* status pills */
.status {
  display: inline-flex;
  align-items: center;
  gap: 0.45rem;
  font-size: 0.72rem;
  font-weight: 680;
  letter-spacing: 0.09em;
  text-transform: uppercase;
  padding: 0.34rem 0.8rem;
  border-radius: 999px;
}
.status::before { content: ""; width: 6px; height: 6px; border-radius: 50%; background: currentColor; }
.status-platform { background: rgba(46, 102, 86, 0.12); color: var(--emerald); }
.status-research { background: rgba(169, 196, 210, 0.28); color: #33596B; }
.status-dev      { background: rgba(210, 162, 76, 0.16); color: var(--copper); }
.status-capability { background: rgba(18, 38, 44, 0.08); color: var(--ink); }
.status-commercial { background: rgba(176, 118, 59, 0.14); color: var(--copper); }

/* dark cards */
.card-dark {
  background: rgba(247, 244, 236, 0.045);
  border: 1px solid var(--line-dark);
  border-radius: var(--radius);
  padding: clamp(1.5rem, 2.4vw, 2.1rem);
  transition: transform 0.35s ease, background 0.35s ease, border-color 0.35s ease;
}
.card-dark:hover { transform: translateY(-5px); background: rgba(247, 244, 236, 0.075); border-color: rgba(210, 162, 76, 0.4); }
.card-dark .h3 { color: var(--ivory); margin-bottom: 0.55rem; }
.card-dark p { color: rgba(247, 244, 236, 0.72); font-size: 0.97rem; }
.card-dark .num {
  font-family: var(--serif);
  font-size: 1.05rem;
  color: var(--gold);
  display: block;
  margin-bottom: 0.9rem;
}

/* Split feature */
.split {
  display: grid;
  grid-template-columns: 1.05fr 1fr;
  gap: clamp(2.2rem, 5vw, 4.5rem);
  align-items: center;
}
.split.rev { grid-template-columns: 1fr 1.05fr; }
.split.rev .split-media { order: 2; }
@media (max-width: 900px) {
  .split, .split.rev { grid-template-columns: 1fr; }
  .split.rev .split-media { order: 0; }
}
.split-media {
  position: relative;
  border-radius: calc(var(--radius) + 6px);
  overflow: hidden;
  box-shadow: var(--shadow-soft);
}
.split-media img { width: 100%; height: 100%; object-fit: cover; transform: scale(1.02); transition: transform 1.2s ease; }
.split-media:hover img { transform: scale(1.07); }
.split-media::after {
  content: "";
  position: absolute; inset: 0;
  background: linear-gradient(to top, rgba(8, 20, 24, 0.35), transparent 45%);
}
.media-tag {
  position: absolute;
  z-index: 2;
  bottom: 1.1rem; left: 1.1rem;
  font-size: 0.74rem;
  font-weight: 650;
  letter-spacing: 0.14em;
  text-transform: uppercase;
  color: var(--ivory);
  background: rgba(8, 20, 24, 0.55);
  -webkit-backdrop-filter: blur(8px);
  backdrop-filter: blur(8px);
  border: 1px solid rgba(247, 244, 236, 0.18);
  padding: 0.45rem 0.9rem;
  border-radius: 999px;
}

/* checklist */
.checks { display: grid; gap: 0.85rem; margin-top: 1.6rem; }
.checks li {
  display: flex;
  gap: 0.85rem;
  align-items: flex-start;
  font-size: 1rem;
  color: var(--charcoal);
}
.checks li strong { color: var(--ink); }
.checks .tick {
  flex: none;
  width: 22px; height: 22px;
  margin-top: 0.15rem;
  border-radius: 50%;
  display: grid;
  place-items: center;
  background: rgba(46, 102, 86, 0.14);
  color: var(--emerald);
}
.checks .tick svg { width: 12px; height: 12px; }
.on-dark .checks li { color: rgba(247, 244, 236, 0.85); }
.on-dark .checks li strong { color: var(--ivory); }
.on-dark .checks .tick { background: rgba(210, 162, 76, 0.18); color: var(--gold); }

/* ============================================================
   PROCESS TIMELINE
   ============================================================ */
.process { position: relative; margin-top: 1rem; }
.process-track {
  display: grid;
  grid-template-columns: repeat(7, 1fr);
  gap: 1.1rem;
  position: relative;
}
.process-track::before {
  content: "";
  position: absolute;
  top: 26px; left: 3%; right: 3%;
  height: 1.5px;
  background: var(--line-dark);
}
.process-track::after {
  content: "";
  position: absolute;
  top: 26px; left: 3%; right: 3%;
  height: 1.5px;
  background: linear-gradient(90deg, var(--gold), var(--aqua));
  transform: scaleX(0);
  transform-origin: left;
  transition: transform 2.6s cubic-bezier(0.22, 1, 0.36, 1);
}
.process.in .process-track::after { transform: scaleX(1); }
.process-step { text-align: center; position: relative; padding-top: 0; }
.process-dot {
  width: 52px; height: 52px;
  margin: 0 auto 1rem;
  border-radius: 50%;
  display: grid;
  place-items: center;
  background: var(--teal-800);
  border: 1.5px solid var(--line-dark);
  color: var(--gold);
  font-family: var(--serif);
  font-size: 1.05rem;
  position: relative;
  z-index: 2;
  transition: border-color 0.4s ease, box-shadow 0.4s ease, transform 0.4s ease;
}
.process-step:hover .process-dot { border-color: var(--gold); transform: scale(1.08); box-shadow: 0 0 0 8px rgba(210, 162, 76, 0.08); }
.process-step h4 { color: var(--ivory); font-family: var(--sans); font-size: 0.92rem; font-weight: 640; margin-bottom: 0.3rem; }
.process-step p { color: rgba(247, 244, 236, 0.6); font-size: 0.8rem; line-height: 1.5; }
@media (max-width: 980px) {
  .process-track { grid-template-columns: 1fr; gap: 0; }
  .process-track::before, .process-track::after { left: 25px; right: auto; top: 2%; bottom: 2%; width: 1.5px; height: auto; }
  .process-track::after { background: linear-gradient(to bottom, var(--gold), var(--aqua)); transform: scaleY(0); transform-origin: top; }
  .process.in .process-track::after { transform: scaleY(1); }
  .process-step { display: flex; gap: 1.2rem; text-align: left; align-items: flex-start; padding-block: 0.9rem; }
  .process-dot { margin: 0; flex: none; }
}

/* ============================================================
   DUAL PATHWAY (Wellness within / Renewal without)
   ============================================================ */
.dual { display: grid; grid-template-columns: 1fr 1fr; gap: clamp(1.2rem, 2.4vw, 2rem); }
@media (max-width: 860px) { .dual { grid-template-columns: 1fr; } }
.pathway {
  position: relative;
  border-radius: calc(var(--radius) + 4px);
  padding: clamp(2rem, 3.4vw, 3rem);
  min-height: 380px;
  display: flex;
  flex-direction: column;
  justify-content: flex-end;
  overflow: hidden;
  color: var(--ivory);
  transition: transform 0.4s ease, box-shadow 0.4s ease;
}
.pathway:hover { transform: translateY(-6px); box-shadow: var(--shadow-soft); }
.pathway-bg {
  position: absolute; inset: 0;
  width: 100%; height: 100%;
  object-fit: cover;
  opacity: 0.5;
  z-index: 0;
  transition: transform 0.7s ease, opacity 0.4s ease;
}
.pathway:hover .pathway-bg { transform: scale(1.06); opacity: 0.62; }
.pathway::after {
  content: "";
  position: absolute; inset: 0;
  background: linear-gradient(to top, rgba(8, 20, 24, 0.94) 18%, rgba(8, 20, 24, 0.3) 70%, rgba(8, 20, 24, 0.15));
  z-index: 1;
}
.pathway > *:not(.pathway-bg) { position: relative; z-index: 2; }
.pathway-a { background: radial-gradient(700px 420px at 80% 0%, rgba(210, 162, 76, 0.3), transparent 60%), linear-gradient(155deg, var(--teal-800), var(--navy-950)); }
.pathway-b { background: radial-gradient(700px 420px at 20% 0%, rgba(143, 189, 182, 0.28), transparent 60%), linear-gradient(205deg, var(--teal-700), var(--navy-950)); }
.pathway .k {
  font-size: 0.75rem;
  letter-spacing: 0.24em;
  text-transform: uppercase;
  font-weight: 650;
  color: var(--gold);
  margin-bottom: 0.7rem;
}
.pathway h3 { color: var(--ivory); font-size: clamp(1.6rem, 2.6vw, 2.2rem); margin-bottom: 0.7rem; }
.pathway p { color: rgba(247, 244, 236, 0.75); max-width: 46ch; font-size: 0.98rem; }
.pathway .orb {
  position: absolute;
  top: -60px; right: -60px;
  width: 240px; height: 240px;
  border-radius: 50%;
  border: 1px solid rgba(210, 162, 76, 0.25);
  background: radial-gradient(circle at 35% 35%, rgba(210, 162, 76, 0.16), transparent 60%);
  transition: transform 0.6s ease;
}
.pathway-b .orb { border-color: rgba(143, 189, 182, 0.3); background: radial-gradient(circle at 35% 35%, rgba(143, 189, 182, 0.16), transparent 60%); right: auto; left: -60px; }
.pathway:hover .orb { transform: scale(1.15); }

/* ============================================================
   LIPOSOME MICRO-ANIMATION (CSS)
   ============================================================ */
.liposome-fig {
  position: relative;
  width: min(300px, 70vw);
  aspect-ratio: 1;
  margin-inline: auto;
}
.liposome-fig .ring {
  position: absolute;
  inset: 0;
  border-radius: 50%;
  border: 1.5px dashed rgba(143, 189, 182, 0.55);
  animation: spin 40s linear infinite;
}
.liposome-fig .ring.r2 { inset: 13%; border-style: solid; border-color: rgba(210, 162, 76, 0.4); animation-duration: 30s; animation-direction: reverse; }
.liposome-fig .ring.r3 { inset: 26%; border-style: dashed; border-color: rgba(143, 189, 182, 0.4); animation-duration: 22s; }
.liposome-fig .core {
  position: absolute;
  inset: 38%;
  border-radius: 50%;
  background: radial-gradient(circle at 35% 30%, var(--gold-bright), var(--copper) 70%);
  box-shadow: 0 0 60px rgba(210, 162, 76, 0.5);
  animation: corePulse 4.5s ease-in-out infinite;
}
@keyframes spin { to { transform: rotate(360deg); } }
@keyframes corePulse {
  0%, 100% { transform: scale(1); box-shadow: 0 0 46px rgba(210,162,76,0.4); }
  50% { transform: scale(1.07); box-shadow: 0 0 80px rgba(210,162,76,0.62); }
}

/* ============================================================
   EVIDENCE LADDER
   ============================================================ */
.ladder { display: grid; gap: 0.7rem; counter-reset: lad; }
.ladder li {
  display: flex;
  align-items: center;
  gap: 1.1rem;
  background: var(--white);
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 1rem 1.3rem;
  transition: transform 0.3s ease, border-color 0.3s ease;
}
.ladder li:hover { transform: translateX(6px); border-color: rgba(176, 118, 59, 0.4); }
.ladder li::before {
  counter-increment: lad;
  content: "0" counter(lad);
  font-family: var(--serif);
  color: var(--copper);
  font-size: 1.05rem;
  flex: none;
}
.ladder li strong { display: block; color: var(--ink); font-size: 0.98rem; }
.ladder li span { color: var(--slate); font-size: 0.88rem; line-height: 1.5; }

/* ============================================================
   TEAM
   ============================================================ */
.team-grid { display: grid; grid-template-columns: repeat(4, 1fr); gap: clamp(1.2rem, 2.2vw, 1.8rem); }
.advisor-grid { display: grid; grid-template-columns: repeat(2, 1fr); gap: clamp(1.2rem, 2.2vw, 1.8rem); max-width: 760px; }
@media (max-width: 1020px) { .team-grid { grid-template-columns: repeat(2, 1fr); } }
@media (max-width: 560px) { .team-grid, .advisor-grid { grid-template-columns: 1fr; } }
.person {
  background: var(--white);
  border: 1px solid var(--line);
  border-radius: var(--radius);
  padding: 2rem 1.6rem 1.8rem;
  text-align: center;
  transition: transform 0.35s ease, box-shadow 0.35s ease, border-color 0.35s ease;
}
.person:hover { transform: translateY(-6px); box-shadow: var(--shadow-soft); border-color: rgba(176, 118, 59, 0.35); }
.avatar {
  width: 124px; height: 124px;
  margin: 0 auto 1.2rem;
  border-radius: 50%;
  display: grid;
  place-items: center;
  font-family: var(--serif);
  font-size: 1.9rem;
  color: var(--ivory);
  background: linear-gradient(140deg, var(--teal-800), var(--emerald));
  position: relative;
  overflow: visible;
}
.avatar img {
  width: 100%; height: 100%;
  object-fit: cover;
  border-radius: 50%;
  filter: saturate(0.96);
  transition: transform 0.4s ease;
}
.person:hover .avatar img { transform: scale(1.05); }
.person .cred {
  display: block;
  font-size: 0.76rem;
  color: var(--slate-light);
  letter-spacing: 0.02em;
  margin-bottom: 0.7rem;
  line-height: 1.45;
}
.avatar::after {
  content: "";
  position: absolute;
  inset: -6px;
  border-radius: 50%;
  border: 1.5px solid rgba(210, 162, 76, 0.55);
  transition: transform 0.4s ease, border-color 0.4s ease;
}
.person:hover .avatar::after { transform: scale(1.08); border-color: var(--gold); }
.person.advisor .avatar { background: linear-gradient(140deg, var(--copper), var(--gold)); color: var(--navy-950); }
.person h3 { font-size: 1.18rem; margin-bottom: 0.15rem; }
.person .role {
  font-size: 0.78rem;
  font-weight: 680;
  letter-spacing: 0.13em;
  text-transform: uppercase;
  color: var(--copper);
  display: block;
  margin-bottom: 0.75rem;
}
.person p { font-size: 0.9rem; color: var(--slate); line-height: 1.6; }

/* ============================================================
   PIPELINE TABLE
   ============================================================ */
.pipeline { display: grid; gap: 0.8rem; }
.pipeline-row {
  display: grid;
  grid-template-columns: 1.6fr 1fr auto;
  gap: 1.2rem;
  align-items: center;
  background: var(--white);
  border: 1px solid var(--line);
  border-radius: var(--radius-sm);
  padding: 1.15rem 1.5rem;
  transition: transform 0.3s ease, border-color 0.3s ease, box-shadow 0.3s ease;
}
.pipeline-row:hover { transform: translateX(6px); border-color: rgba(176,118,59,0.4); box-shadow: var(--shadow-card); }
.pipeline-row strong { color: var(--ink); font-size: 1rem; }
.pipeline-row .area { color: var(--slate); font-size: 0.88rem; }
@media (max-width: 760px) {
  .pipeline-row { grid-template-columns: 1fr; gap: 0.5rem; }
}

/* ============================================================
   CTA BAND
   ============================================================ */
.cta-band {
  position: relative;
  overflow: hidden;
  border-radius: calc(var(--radius) + 8px);
  background:
    radial-gradient(900px 460px at 85% 10%, rgba(210, 162, 76, 0.24), transparent 55%),
    radial-gradient(700px 400px at 10% 90%, rgba(46, 102, 86, 0.35), transparent 55%),
    linear-gradient(150deg, var(--navy-950), var(--teal-800));
  color: var(--ivory);
  padding: clamp(2.8rem, 6vw, 5rem);
  text-align: center;
}
.cta-band .h2 { color: var(--ivory); max-width: 22ch; margin-inline: auto; }
.cta-band .lead { max-width: 58ch; margin: 1.2rem auto 2.2rem; }
.cta-tags { display: flex; flex-wrap: wrap; gap: 0.6rem; justify-content: center; margin-top: 2.2rem; }
.cta-tags a {
  font-size: 0.83rem;
  font-weight: 600;
  padding: 0.5rem 1.05rem;
  border-radius: 999px;
  border: 1px solid rgba(247, 244, 236, 0.25);
  color: rgba(247, 244, 236, 0.85);
  transition: border-color 0.3s ease, color 0.3s ease, background 0.3s ease;
}
.cta-tags a:hover { border-color: var(--gold); color: var(--gold-bright); background: rgba(210, 162, 76, 0.08); }

/* ============================================================
   CONTACT
   ============================================================ */
.contact-card {
  background: var(--white);
  border: 1px solid var(--line);
  border-radius: var(--radius);
  padding: 2rem;
  transition: transform 0.3s ease, box-shadow 0.3s ease;
}
.contact-card:hover { transform: translateY(-5px); box-shadow: var(--shadow-soft); }
.contact-card .h3 { margin-bottom: 0.4rem; }
.contact-card p { color: var(--slate); font-size: 0.95rem; margin-bottom: 1rem; }
.contact-card a.big {
  font-family: var(--serif);
  font-size: 1.25rem;
  color: var(--ink);
  transition: color 0.25s ease;
}
.contact-card a.big:hover { color: var(--copper); }

/* ============================================================
   FOOTER
   ============================================================ */
.site-footer {
  background: var(--navy-950);
  color: rgba(247, 244, 236, 0.72);
  padding: clamp(3.5rem, 7vw, 5.5rem) 0 2.2rem;
  position: relative;
  overflow: hidden;
}
.footer-grid {
  display: grid;
  grid-template-columns: 1.6fr 1fr 1fr 1.2fr;
  gap: clamp(2rem, 4vw, 3.5rem);
  padding-bottom: 3rem;
  border-bottom: 1px solid var(--line-dark);
}
@media (max-width: 940px) { .footer-grid { grid-template-columns: 1fr 1fr; } }
@media (max-width: 560px) { .footer-grid { grid-template-columns: 1fr; } }
.footer-brand p { font-size: 0.95rem; max-width: 38ch; margin-top: 1rem; color: rgba(247, 244, 236, 0.6); }
.footer-tagline { font-family: var(--serif); font-style: italic; color: var(--gold); font-size: 1.05rem; margin-top: 1.1rem; }
.site-footer h4 {
  color: var(--ivory);
  font-size: 0.8rem;
  font-weight: 680;
  letter-spacing: 0.18em;
  text-transform: uppercase;
  margin-bottom: 1.1rem;
}
.site-footer ul { display: grid; gap: 0.55rem; }
.site-footer ul a { font-size: 0.93rem; color: rgba(247, 244, 236, 0.66); transition: color 0.25s ease; }
.site-footer ul a:hover { color: var(--gold-bright); }
.footer-note {
  margin-top: 2rem;
  display: flex;
  flex-wrap: wrap;
  justify-content: space-between;
  gap: 1rem;
  font-size: 0.8rem;
  color: rgba(247, 244, 236, 0.42);
}
.footer-disclaimer {
  margin-top: 1.6rem;
  font-size: 0.78rem;
  line-height: 1.6;
  color: rgba(247, 244, 236, 0.4);
  max-width: 90ch;
}

/* ============================================================
   REVEAL ANIMATIONS
   ============================================================ */
.reveal {
  opacity: 0;
  transform: translateY(30px);
  transition: opacity 0.9s cubic-bezier(0.22, 1, 0.36, 1), transform 0.9s cubic-bezier(0.22, 1, 0.36, 1);
  transition-delay: var(--d, 0s);
  will-change: opacity, transform;
}
.reveal.in { opacity: 1; transform: translateY(0); }
.reveal-scale {
  opacity: 0;
  transform: scale(0.94);
  transition: opacity 1s ease, transform 1s cubic-bezier(0.22, 1, 0.36, 1);
  transition-delay: var(--d, 0s);
}
.reveal-scale.in { opacity: 1; transform: scale(1); }

/* Reduced motion */
@media (prefers-reduced-motion: reduce) {
  html { scroll-behavior: auto; }
  *, *::before, *::after {
    animation-duration: 0.01ms !important;
    animation-iteration-count: 1 !important;
    transition-duration: 0.01ms !important;
  }
  .reveal, .reveal-scale { opacity: 1 !important; transform: none !important; }
  .hero-canvas, .page-hero-canvas { display: none; }
}

/* utility */
.mt-1 { margin-top: 1rem; }
.mt-2 { margin-top: 2rem; }
.mt-3 { margin-top: 3rem; }
.mb-2 { margin-bottom: 2rem; }
.center { text-align: center; }
.gold { color: var(--gold); }
.copper { color: var(--copper); }
.small-note { font-size: 0.85rem; color: var(--slate-light); font-style: italic; }
.on-dark .small-note { color: rgba(247, 244, 236, 0.45); }
